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Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
Side effects may include trouble sleeping and weight gain. [2] While there are concerns that use during pregnancy results in a 0.2% increased risk of neural tube defects in the baby, this does not rule out its use. [2] Use remains recommended after the first trimester. [2] It should not be used with dofetilide. [3]
Pretomanid is an antibiotic medication used for the treatment of multi-drug-resistant tuberculosis affecting the lungs. [4] [5] It is generally used together with bedaquiline and linezolid. [4] It is taken by mouth. [4] The most common side effects include nerve damage, acne, vomiting, headache, low blood sugar, diarrhea, and liver inflammation ...
Bedaquiline, sold under the brand name Sirturo, is a medication used for the treatment of active tuberculosis. [1] Specifically, it is used to treat multi-drug-resistant tuberculosis along with other medications for tuberculosis. [1] [8] [9] It is taken by mouth. [3] Common side effects include nausea, joint pains, headaches, and chest pain. [1]
There is some efficacy for linezolid to treat those with XDR-TB but side effects and discontinuation of medications were common. [160] [161] Bedaquiline is tentatively supported for use in multiple drug-resistant TB. [162] XDR-TB is a term sometimes used to define extensively resistant TB, and constitutes one in ten cases of MDR-TB. Cases of ...
The principles of treatment for MDR-TB and for XDR-TB are the same. Second-line drugs are more toxic than the standard anti-TB regimen and can cause a range of serious side-effects including hepatitis, depression, hallucinations, and deafness. [14] Patients are often hospitalized for long periods, in isolation.
Delamanid is sold under the brand name Deltyba, is a medication used to treat tuberculosis. [2] Specifically it is used, along with other antituberculosis medications, for active multidrug-resistant tuberculosis. [2] It is taken by mouth. [2] There are common side effects which include headache, dizziness, and nausea. [3]
Isoniazid can be used alone or in combination with Rifampin for treatment of latent tuberculosis, or as part of a four-drug regimen for treatment of active tuberculosis. [18] The drug regimen typically requires daily or weekly oral administration for a period of three to nine months, often under Directly Observed Therapy (DOT) supervision. [18]