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The pathophysiology of MND, or dementia, varies depending on the subtype. Most types, except vascular dementia, are caused by the accumulation of native proteins in the brain. Alzheimer disease is characterized by widespread atrophy of the cortex and deposition of amyloid plaques, and neurofibrillary tangles of hyperphosphorylated tau protein ...
Dementia is a term used to describe a group of symptoms affecting memory, thinking and social abilities. In people who have dementia, the symptoms interfere with their daily lives. Dementia isn't one specific disease. Several diseases can cause dementia. Dementia generally involves memory loss.
Dementia is the loss of cognitive functioning — thinking, remembering, and reasoning — to such an extent that it interferes with a person's daily life and activities. Some people with dementia cannot control their emotions, and their personalities may change.
Alzheimer’s disease is the most common form of dementia and the most common neurodegenerative disease. It manifests as a decline in short-term memory and cognition that impairs daily behavior.
The pathophysiology of dementia is broadly characterised by the aggregation of misfolded proteins (such as amyloid-β plaques and neurofibrillary tangles in Alzheimer's disease) and cerebrovascular disease.
Dementia is a syndrome that can be caused by a number of diseases which over time destroy nerve cells and damage the brain, typically leading to deterioration in cognitive function (i.e. the ability to process thought) beyond what might be expected from the usual consequences of biological ageing.
16 min read. What Is Dementia? Dementia, also called major neurocognitive disorder, isn’t a disease. It's a group of symptoms caused by other conditions. Dementia is an umbrella term for a loss...
Dementia - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.
This article provides an overview of the pathophysiological processes in the most common types of dementia in older adults and highlights some of the important developments in the use of biomarkers in the clinical diagnosis of dementia.
Alzheimer’s disrupts processes vital to neurons and their networks, including communication, metabolism, and repair. At first, Alzheimer’s usually damages the connections among neurons in parts of the brain involved in memory, including the entorhinal cortex and hippocampus.