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In United States Pharmacopeia (USP) General Chapter <711> Dissolution, there are four dissolution apparatuses standardized and specified. [6] They are: USP Dissolution Apparatus 1 – Basket (37 °C ± 0.5 °C ) USP Dissolution Apparatus 2 – Paddle (37 °C ± 0.5 °C) USP Dissolution Apparatus 3 – Reciprocating Cylinder (37 °C ± 0.5 °C)
I think it would make the article clearer if "dissolution" was explained. CBHA 03:22, 10 May 2013 (UTC) [] @CBHA: A good suggestion but I disagree. Dissolution testing is a common name used in the Pharma industry, it should be pretty self-evident to most readers what dissolution means even if your not sure or don't work in that field ( a simple Google search can rectify any doubts).
The solubility classification is based on a United States Pharmacopoeia (USP) aperture. The intestinal permeability classification is based on a comparison to the intravenous injection. All those factors are highly important because 85% of the most sold drugs in the United States and Europe are orally administered. [citation needed]
The USP is published in a combined volume with the National Formulary (a formulary) as the USP-NF. [2] If a drug ingredient or drug product has an applicable USP quality standard (in the form of a USP-NF monograph), it must conform in order to use the designation "USP" or "NF".
In pharmaceutics, sink condition is a term mostly related to the dissolution testing procedure.. It means using a sheer volume of solvent, usually about 5 to 10 times greater than the volume present in the saturated solution of the targeted chemical (often the API, and sometimes the excipients) contained in the dosage form being tested.
Particle size and surface area influence the release of a drug from a dosage form that is administered orally, rectally, parenterally, and topically.Higher surface area brings about intimate contact of the drug with the dissolution fluids in vivo and increases the drug solubility and dissolution.
According to Method 5210 in Standard Methods for the Examination of Water and Wastewater, the BOD bottle should include a ground-glass stopper and a flared mouth which form a water seal preventing the air from the outside of the bottle coming in. [1] Method 5210 also recommends to use a paper, a foil or a plastic cup to cap over the mouth of ...
Tablet hardness testing is a laboratory technique used by the pharmaceutical industry to determine the breaking point and structural integrity of a tablet and find out how it changes "under conditions of storage, transportation, packaging and handling before usage" [1] The breaking point of a tablet is based on its shape. [2]