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Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters. The three major classes are serotonin transporters (SERTs), dopamine transporters (DATs), and norepinephrine transporters (NETs) and are responsible for the reuptake of their ...
A monoamine reuptake inhibitor (MRI) [1] is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).
Obsessional defences refer to mental techniques that individuals utilize to cope with anxiety by exerting control over their thoughts, emotions, or behaviors. People may rely on strict routines, a desire for perfection, or a strong need for order to maintain a sense of control and avoid facing uncertainty or undesirable impulses.
In Kamin's blocking effect [1] the conditioning of an association between two stimuli, a conditioned stimulus (CS) and an unconditioned stimulus (US) is impaired if, during the conditioning process, the CS is presented together with a second CS that has already been associated with the unconditioned stimulus.
SLC18A2 is essential for enabling the release of neurotransmitters from the axon terminals of monoamine neurons into the synaptic cleft.If SLC18A2 function is inhibited or compromised, monoamine neurotransmitters such as dopamine cannot be released into the synapse via typical release mechanisms (i.e., exocytosis resulting from action potentials).
For addicts, cravings override all normal rules of behavior. In interviews throughout Northern Kentucky, addicts and their families described the insanity that takes hold. Some addicts shared stories of shooting up behind the wheel while driving down Interstate 75 out of Cincinnati, or pulling over at an early exit, a Kroger parking lot.
The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons.It transports monoamine neurotransmitters – such as dopamine, serotonin, norepinephrine, epinephrine, and histamine – into the vesicles, which release the neurotransmitters into synapses, as chemical messages to postsynaptic neurons.
By Steve Holland and David Brunnstrom. WASHINGTON (Reuters) -U.S. President-elect Donald Trump has invited Chinese President Xi Jinping and other foreign leaders to his inauguration next month in ...
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