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[24] [25] [26] Erythromycin is the antibiotic of choice for severe acne, barring the use of its estolate salt which risks maternal hepatotoxicity. [27] Topical nicotinamide and topical zinc are safe, however, there are no FDA pregnancy category ratings.
Contraindicated in pregnancy: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Minocycline mediates its antibiotic activity by binding to the 30S ribosomal subunit of bacteria and thereby inhibiting protein synthesis. [67] [68] It is primarily bacteriostatic. [2] The drug is a broad-spectrum antibiotic and shows activity against a wide range of both Gram-positive and Gram-negative bacteria. [67] [68] [28]
If used during pregnancy, it can cause harm to the developing fetus. [5] However, it appears to be safe for use during breastfeeding. [8] Gentamicin is a type of aminoglycoside [5] and works by disrupting the ability of the bacteria to make proteins, which typically kills the bacteria. [5]
Clarithromycin, sold under the brand name Biaxin among others, is an antibiotic used to treat various bacterial infections. [6] This includes strep throat, pneumonia, skin infections, H. pylori infection, and Lyme disease, among others. [6] Clarithromycin can be taken by mouth as a tablet or liquid or can be infused intravenously. [6]
Tetracycline, sold under various brand names, is an antibiotic in the tetracyclines family of medications, used to treat a number of infections, [3] including acne, cholera, brucellosis, plague, malaria, and syphilis. [3]
Use in pregnancy or breastfeeding appears to generally be safe. [6] ... For β-lactam antipseudomonal antibiotics, ...
Kanamycin A, [2] often referred to simply as kanamycin, is an antibiotic used to treat severe bacterial infections and tuberculosis. [3] It is not a first line treatment. [3] It is used by mouth, injection into a vein, or injection into a muscle. [3] Kanamycin is recommended for short-term use only, usually from 7 to 10 days. [3]