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Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]
Janssen Pharms' Xarelto is prescribed to reduce the risk of stroke and blood clots and treat existing blood clots, and reduce the risk for patients with coronary or peripheral artery disease. In ...
Antistasin, the first discovered naturally occurring direct Xa inhibitor Rivaroxaban, the first synthetic direct Xa inhibitor marketed as a drug Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood ...
Download as PDF; Printable version; In other projects Appearance. move to sidebar hide. From Wikipedia, the free encyclopedia. Redirect page. Redirect to: Rivaroxaban;
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Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.
Counsel for Defendant Janssen Pharma., J&J, and Janssen Research & Development 3 (Pledger v Janssen, et al.) APPEARANCES: (Continued) WEIL, GOTSHAL & MANGES, LLP BY: DIANE P. SULLIVAN, ESQUIRE ALLISON BROWN, ESQUIRE (admitted pro hac vice) 301 Carnegie Center, Suite 303 Princeton, New Jersey 08540 T: 609-986-1100 F: 212-310-8007
John J. Kurz, RMR-CRR, Official Court Reporter Phone 215-683-8035 Fax 215-683-8005 - BENITA PLEDGER - CROSS - 94 1 seated. 2 All right.
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