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The lateral spinothalamic tract (or lateral spinothalamic fasciculus), is a bundle of afferent nerve fibers ascending through the white matter of the spinal cord, in the spinothalamic tract, carrying sensory information to the brain. It carries pain, and temperature sensory information (protopathic sensation) to the thalamus.
The cutaneous receptors of the skin project in an orderly fashion to the spinal cord, and from there, via different afferent pathways (dorsal column-medial lemniscus tract and spinothalamic tract), to the ventral posterior nucleus of the thalamus and the primary somatosensory cortex. Again, adjacent areas on the skin are represented by adjacent ...
Midline intralaminar nuclei receive afferents from the brain stem, spinal cord, and cerebellum. Connections with the cerebral cortex and basal nuclei are reciprocal. Afferents from the spinothalamic tract as well as periaqueductal gray are part of a pathway involved in pain processing. [3]
The spinothalamic tract is a sensory pathway originating in the spinal cord. It transmits information to the thalamus about pain, temperature, itch and crude touch . There are two main parts: the lateral spinothalamic tract , which transmits pain and temperature, and the anterior (or ventral) spinothalamic tract , which transmits crude touch ...
The dynamic interactions between Spinal cord and sensory input are ensured by modulating transmission in locomotor pathways in a state- and phase-dependent manner. For instance, proprioceptive inputs from extensors can, during stance, adjust the timing and amplitude of muscle activities of the limbs to the speed of locomotion but be silenced ...
The tract transmits slow nociceptive/pain information (but thermal, and crude touch information as well) from the spinal cord to reticular formation which in turn relays the information to the thalamus via reticulothalamic fibers as well as to other parts of the brain (as opposed to the spinothalamic tract - the direct pathway of the ...
The ventral posterolateral nucleus (VPL) is one of the subdivisions of the ventral posterior nucleus in the ventral nuclear group of the thalamus. [1] It relays sensory information from the second-order neurons of the neospinothalamic tract and medial lemniscus (of the dorsal column-medial lemniscus pathway) which synapse with the third-order neurons in the nucleus.
The substantia gelatinosa is one point (the nucleus proprius being the other) where first order neurons of the spinothalamic tract synapse. Many μ and κ-opioid receptors, presynaptic and postsynaptic, are found on these nerve cells; they can be targeted to manage pain of distal origin. For instance, neuraxial administration of opioids results ...