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  2. Delirium tremens - Wikipedia

    en.wikipedia.org/wiki/Delirium_tremens

    Delirium tremens is a component of alcohol withdrawal hypothesized to be the result of compensatory changes in response to chronic heavy alcohol use. Alcohol positively allosterically modulates the binding of GABA , enhancing its effect and resulting in inhibition of neurons projecting into the nucleus accumbens , as well as inhibiting NMDA ...

  3. Alcohol withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Alcohol_withdrawal_syndrome

    Alcoholics who have had two or more alcohol withdrawals show more frontal lobe cognitive dysfunction than those who have experienced one or no prior withdrawals. Kindling of neurons is the proposed cause of withdrawal-related cognitive damage. Kindling from repeated withdrawals leads to accumulating neuroadaptive changes.

  4. Disulfiram - Wikipedia

    en.wikipedia.org/wiki/Disulfiram

    Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.

  5. Keeley Institute - Wikipedia

    en.wikipedia.org/wiki/Keeley_Institute

    The Keeley Institute, known for its Keeley Cure or Gold Cure, was a commercial medical operation that offered treatment to alcoholics from 1879 to 1965. Though at one time there were more than 200 branches in the United States and Europe, the original institute was founded by Leslie Keeley in Dwight, Illinois , United States .

  6. Post-acute-withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

    Benzodiazepines, opioids, alcohol, and any other drug may induce prolonged withdrawal and have similar effects, with symptoms sometimes persisting for years after cessation of use. Psychosis including severe anxiety and depression are commonly induced by sustained alcohol, opioid, benzodiazepine, and other drug use which in most cases abates ...

  7. Acamprosate - Wikipedia

    en.wikipedia.org/wiki/Acamprosate

    Acamprosate is a medication that works in the brain to treat alcohol use disorder. Acamprosate works by decreasing cravings and urges to use alcohol. This allows people who take the medication to control urges to drink and help to continue to not use alcohol. Acamprosate does not help with symptoms of alcohol withdrawal.

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