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Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
Cushing syndrome can be hard to diagnose. Here's what it is, as well as what causes it and how it's treated.
According to the Mayo Clinic, symptoms of Cushing syndrome include a rounded face, stretch marks and a fatty lump between the shoulders; the condition can also lead to high blood pressure and bone ...
Exogenous corticosteroid use: Exogenous corticosteroids suppress the stimulation of the hypothalamus and the pituitary gland to secrete CRH and ACTH, respectively. [2] [3] These cases may present with symptoms of cortisol excess (see Cushing's syndrome). [3] Sheehan's syndrome: Loss of blood flow to the pituitary gland following childbirth [2]
Iatrogenic Cushing's Syndrome is a direct complication of glucocorticoid therapy, and the most common cause of exogenous Cushing's Syndrome. [25] Clinical features of Cushing's Syndrome are inclusive of many adverse effects in glucocorticoid therapy. [25] Traditional symptoms include weight gain, myopathy, osteoporosis, increased risk of ...
Exogenous Cushing syndrome is brought on by taking glucocorticoid medicines, which are typically used to treat inflammatory diseases and pain, according to the Mayo Clinic. This is the version ...
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[35] [36] Cushing's syndrome can either be exogenous or endogenous, depending on whether it is caused by an external or internal source, respectively. [37] The intake of glucocorticoids, a type of corticosteroid, is a common cause for the development of exogenous Cushing's syndrome. Endogenous Cushing's syndrome can occur when the body produces ...
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