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Intracellular bacteria are bacteria that have the capability to enter and survive within the cells of the host organism. [1] These bacteria include many different pathogens that live in the cytoplasm and nuclei of the host cell's they inhabit. Two examples of intracellular pathogenic bacteria are Mycobacterium tuberculosis and also Toxoplasma ...
When an intracellular parasite goes to enter a host cell, it is particular about the type of host cell. This is because most intracellular parasites are able to infect only a few different cell types. [21] Viruses use a number of host receptors to gain entry to the cell, usually by causing endocytosis. [7]
In comparison to eukaryotes, the intracellular features of the bacterial cell are extremely simple. Bacteria do not contain organelles in the same sense as eukaryotes. Instead, the chromosome and perhaps ribosomes are the only easily observable intracellular structures found in all bacteria. There do exist, however, specialized groups of ...
Cell-based models are mathematical models that represent biological cells as discrete entities. Within the field of computational biology they are often simply called agent-based models [1] of which they are a specific application and they are used for simulating the biomechanics of multicellular structures such as tissues. to study the influence of these behaviors on how tissues are organised ...
Due to the wide range of obligate parasite types, it is impossible to identify a general invasion strategy. Intracellular parasites use various strategies to invade cells and subvert cellular signalling pathways. Most bacteria and viruses undergo passive uptake, where they rely on the host cell for uptake.
As obligate intracellular parasites, they must live and reproduce within an animal cell. Coccidian parasites infect the intestinal tracts of animals, [2] and are the largest group of apicomplexan protozoa. Infection with these parasites is known as coccidiosis. Coccidia can infect all mammals, some birds, some fish, some reptiles, and some ...
The ability of intracellular bacteria to migrate between host cells. The ability of the bacteria to kill host cells. This can be measured by several methods, for instance by the LDH -release assay, in which the enzyme LDH, which leaks from dead cells, is identified by measuring its enzymatic activity.
The eukaryotic cell cycle is very complex and is one of the most studied topics, since its misregulation leads to cancers. It is possibly a good example of a mathematical model as it deals with simple calculus but gives valid results. Two research groups [1] [2] have produced several models of the cell cycle simulating several organisms. They ...