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  2. Medication-related osteonecrosis of the jaw - Wikipedia

    en.wikipedia.org/wiki/Medication-related_osteo...

    Bisphosphonates are either administered orally or intravenously. They reduce bone resorption. [31] Mechanism of action: Bisphosphonate binds to the mineral component of the bone and inhibits enzymes (i.e. farnesyl-pyrophosphate synthase) responsible for bone formation, osteoclast recruitment and osteoclast function. [29] [31]

  3. Bisphosphonate - Wikipedia

    en.wikipedia.org/wiki/Bisphosphonate

    Long-term treatment with bisphosphonates produces anti-fracture and bone mineral density effects that persist for 3–5 years after an initial 3–5 years of treatment. [2] The bisphosphonate alendronate reduces the risk of hip, vertebral, and wrist fractures by 35-39%; zoledronate reduces the risk of hip fractures by 38% and of vertebral ...

  4. Alendronic acid - Wikipedia

    en.wikipedia.org/wiki/Alendronic_acid

    The risk is considerably higher for extractions in the mandible (lower jaw) than other areas of the mouth, and the risk increases if you have been taking it for four or more years [12] Although this side effect is uncommon (0.4-1.6% for oral alendronic acid), it occurs primarily in patients being administered intravenous bisphosphonates, with ...

  5. Zoledronic acid - Wikipedia

    en.wikipedia.org/wiki/Zoledronic_acid

    It is given by injection into a vein. [3] Common side effects include fever, joint pain, high blood pressure, diarrhea, and feeling tired. [3] Serious side effects may include kidney problems, low blood calcium, and osteonecrosis of the jaw. [3] Use during pregnancy may result in harm to the baby. [3] It is in the bisphosphonate family of ...

  6. Ibandronic acid - Wikipedia

    en.wikipedia.org/wiki/Ibandronic_acid

    Ibandronic acid is a bisphosphonate medication used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. [4] It may also be used to treat hypercalcemia (elevated blood calcium levels). It is typically formulated as its sodium salt ibandronate sodium. [medical citation needed]

  7. What Is the Maximum Semaglutide Dose for Weight Loss? - AOL

    www.aol.com/maximum-semaglutide-dose-weight-loss...

    The maximum semaglutide dose for weight loss is 2.4 milligrams (mg) per week. Your healthcare provider will start you on a lower weekly dose and gradually increase it over time.

  8. CoolSculpting brought on troubling side effects for ...

    www.aol.com/lifestyle/coolsculpting-brought...

    The official CoolSculpting website lists paradoxical hyperplasia as some of the "rare" additional side effects of CoolSculpting, along with "late onset pain, freeze burn, vasovagal symptoms ...

  9. Postoperative nausea and vomiting - Wikipedia

    en.wikipedia.org/wiki/Postoperative_nausea_and...

    Adverse effects include a transient increase in serum glucose level, and poor wound healing (controversial). Medications include dexamethasone. Butyrophenones are typically administered as a single injection at the end of surgery. Adverse effects include prolongation of the QT interval on EKG. Medications include droperidol and haloperidol.