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Amiodarone has been used both in the treatment of acute life-threatening arrhythmias as well as the long-term suppression of arrhythmias. [13] Amiodarone is commonly used to treat different types of abnormal heart rhythms, such as atrial arrhythmias (supraventricular arrhythmias) and ventricular arrhythmias. [13]
Amiodarone induced thyrotoxicosis (AIT) is a form of hyperthyroidism due to treatment with antiarrhythmic drug, amiodarone. Amiodarone induced thyroid dysfunction more commonly results in hypothyroidism , estimated to occur in 6-32% of patients, whereas hyperthyroidism from amiodarone use is estimated at 1-12%. [ 1 ]
Amiodarone is also safe to use in individuals with cardiomyopathy and atrial fibrillation, to maintain normal sinus rhythm. Amiodarone prolongation of the action potential is uniform over a wide range of heart rates, so this drug does not have reverse use-dependent action. Amiodarone was the first agent described in this class. [4]
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Symptoms often occur without any specific trigger, although some find that their palpitations often occur after lifting heavy items or bending forwards. [1] The onset of palpitations is sudden, with the acceleration of the heart rate occurring within a single beat, and may be preceded by a feeling of the heart skipping a beat.
A resting heart rate of 100 beats per minute or an increase in heart rate of 100 beats per minute with minimal exertion; Excluding any potential secondary causes of sinus tachycardia; Ruling out atrial tachycardias; Palpitations or presyncope (or both) symptoms that have been clearly linked to resting or easily induced sinus tachycardia.
A normal resting heart rate is 60 to 100 beats per minute. A resting heart rate of more than 100 beats per minute is defined as a tachycardia. During an episode of SVT, the heart beats about 150 to 220 times per minute. [9] Specific treatment depends on the type of SVT [5] and can include medications, medical procedures, or surgery. [5]
Palpitations are not always the result of a physical problem with the heart and can be linked to anxiety. [3] However, they may signal a fast or irregular heartbeat. Palpitations can be brief or long-lasting. They can be intermittent or continuous. Other symptoms can include dizziness, shortness of breath, sweating, headaches, and chest pain. [2]