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Silicosis is a form of occupational lung disease caused by inhalation of crystalline silica dust. It is marked by inflammation and scarring in the form of nodular lesions in the upper lobes of the lungs.
The three main types of pneumoconioses are Asbestosis (caused by inhaling asbestos), Silicosis (caused by inhaling silica), and Coal Workers pneumoconioses A.K.A Black Lung (caused by inhaling coal dust). [3] There are other forms called Mixed Dust pneumoconioses (caused by inhaling more than one mineral) and Byssinosis (caused by inhaling ...
Pulmonary siderosis does not usually cause harmful scar tissue formation within the lungs, which is why it said to be non-fibrotic condition, unlike asbestosis for example, and has also been called "benign pneumoconiosis". [2] Mild to moderate scarring of the lungs has been found in unusual cases of pulmonary siderosis.
A hundred times smaller than a grain of sand, silica dust can lead to lung cancer and silicosis, an irreversible scarring and stiffening of the lungs, among other conditions, according to the ...
[1] [2] The three most common types are asbestosis, silicosis, and coal miner's lung. [3] Pneumoconiosis often causes restrictive impairment, [4] although diagnosable pneumoconiosis can occur without measurable impairment of lung function. [1] [2] Depending on extent and severity, it may cause death within months or years, or it may never ...
The cause is unknown, hence the term idiopathic. [2] Risk factors include cigarette smoking, acid reflux disease (GERD), certain viral infections, and genetic predisposition. [1] The underlying mechanism involves scarring of the lungs. [1] Diagnosis requires ruling out other potential causes. [3]
The differential diagnosis includes other types of lung disease that cause similar symptoms and show similar abnormalities on chest radiographs. Some of these diseases cause fibrosis, scarring or honeycomb change. The most common considerations include: chronic hypersensitivity pneumonitis; non-specific interstitial pneumonia; sarcoidosis
MHC class I polypeptide–related sequence A (MICA) is a highly polymorphic cell surface glycoprotein encoded by the MICA gene located within MHC locus. [5] MICA is related to MHC class I and it has similar domain structure, however, it is not associated with β2-microglobulin nor binds peptides as conventional MHC class I molecules do. [ 6 ]
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