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Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes, [1] seen in diseases such as pemphigus vulgaris. [2] It is absent in bullous pemphigoid , making it useful for differential diagnosis .
Orthopedic surgery attempts to recreate the normal anatomy of the fractured bone by reduction of the displacement. [citation needed] This sense of the term "reduction" does not imply any sort of removal or quantitative decrease but rather implies a restoration: re ("back [to initial position]") + ducere ("lead"/"bring"), i.e., "bringing back to ...
Histopathological image of dyshidrotic dermatitis, showing focal spongiotic change in the epidermis. Spongiosis is mainly intercellular [1] edema (abnormal accumulation of fluid) in the epidermis, [2] and is characteristic of eczematous dermatitis, manifested clinically by intraepidermal vesicles (fluid-containing spaces), "juicy" papules, and/or lichenification. [3]
Variable degree of epidermal spongiosis and vesicle formation, filled with proteinaceous fluid containing lymphocytes and histiocytes. Usually superficial dermal edema with perivascular lymphocytic infiltrate, with exocytosis. No acanthosis or parakeratosis. Typical findings: [2] Mild to moderate spongiosis and exocytosis of inflammatory cells
A separate review found that most people would consider a reduction in pain of approximately 12 on the same 0 to 100 scale important—suggesting that for most people, the pain reduction at 3 months is not important. [16] Arthroscopy did not reduce pain or improve function or quality of life at one year. [12] There are important adverse effects ...
The pain can usually be triggered. Common triggers include light touch, eating, talking or putting on make-up. Most patients whose face pain improved with an MVD also improved at least temporarily with medication. In addition to having the proper type of pain, candidates for an MVD must also be healthy enough to undergo surgery.
In cases where closed reduction is not successful, open (surgical) reduction may be needed. [2] X-rays are often used to confirm success and absence of associated fractures. The arm should be kept in a sling or immobilizer for several days, prior to supervised recovery of motion and strength. Various non-operative reduction techniques are employed.
Damage control surgery is surgical intervention to keep the patient alive rather than correct the anatomy. [ 1 ] [ 2 ] It addresses the "lethal triad" for critically ill patients with severe hemorrhage affecting homeostasis leading to metabolic acidosis , hypothermia , and increased coagulopathy .