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  2. Human genetic enhancement - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_enhancement

    Human genetic enhancement. An illustration of viral vector -mediated gene transfer using an adenovirus as the vector. Human genetic enhancement or human genetic engineering refers to human enhancement by means of a genetic modification. This could be done in order to cure diseases (gene therapy), prevent the possibility of getting a particular ...

  3. Human germline engineering - Wikipedia

    en.wikipedia.org/wiki/Human_germline_engineering

    Human germline engineering. Human germline engineering is the process by which the genome of an individual is edited in such a way that the change is heritable. This is achieved by altering the genes of the germ cells, which then mature into genetically modified eggs and sperm. For safety, ethical, and social reasons, there is broad agreement ...

  4. Genetic engineering - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering

    t. e. Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms.

  5. Genome editing - Wikipedia

    en.wikipedia.org/wiki/Genome_editing

    Genome editing. The different generations of nucleases used for genome editing and the DNA repair pathways used to modify target DNA. Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism.

  6. He Jiankui affair - Wikipedia

    en.wikipedia.org/wiki/He_Jiankui_affair

    The He Jiankui affair is a scientific and bioethical controversy concerning the use of genome editing following its first use on humans by Chinese scientist He Jiankui, who edited the genomes of human embryos in 2018. [1][2] He became widely known on 26 November 2018 [3] after he announced that he had created the first human genetically edited ...

  7. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    CRISPR gene editing. CRISPR-Cas9. CRISPR gene editing (CRISPR, pronounced / ˈkrɪspər / "crisper", refers to " c lustered r egularly i nterspaced s hort p alindromic r epeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified. It is based on a simplified version of the bacterial ...

  8. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    Regulations covering genetic modification are part of general guidelines about human-involved biomedical research. [ citation needed ] There are no international treaties which are legally binding in this area, but there are recommendations for national laws from various bodies.

  9. Gene targeting - Wikipedia

    en.wikipedia.org/wiki/Gene_targeting

    Genetic modification usually describes the insertion of a transgene (foreign DNA, i.e. a gene from another species) into a random location within the genome. [ 13 ] [ 14 ] Gene-targeting is a specific biotechnological tool that can lead to small changes to the genome at a specific site [ 2 ] - in which case the edits caused by gene-targeting ...

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