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  2. Central nervous system fatigue - Wikipedia

    en.wikipedia.org/wiki/Central_Nervous_System_Fatigue

    Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.

  3. Allostatic load - Wikipedia

    en.wikipedia.org/wiki/Allostatic_load

    The largest contribution to the allostatic load is the effect of stress on the brain. Allostasis is the system which helps to achieve homeostasis. [18] Homeostasis is the regulation of physiological processes, whereby systems in the body respond to the state of the body and to the external environment. [18]

  4. Central governor - Wikipedia

    en.wikipedia.org/wiki/Central_governor

    The Norwegian mountain runner Jon Tvedt engaging in a strenuous run: it is suggested that the central governor ensures that such endurance exertion does not threaten the body's homeostasis and physical integrity. The central governor is a proposed process in the brain that regulates exercise in regard to a neurally calculated safe exertion by ...

  5. Homeostasis - Wikipedia

    en.wikipedia.org/wiki/Homeostasis

    Thus, to Barcroft homeostasis was not only organized by the brain—homeostasis served the brain. [13] Homeostasis is an almost exclusively biological term, referring to the concepts described by Bernard and Cannon, concerning the constancy of the internal environment in which the cells of the body live and survive.

  6. Fatigue - Wikipedia

    en.wikipedia.org/wiki/Fatigue

    Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...

  7. Muscle fatigue - Wikipedia

    en.wikipedia.org/wiki/Muscle_fatigue

    Muscle fatigue is when muscles that were initially generating a normal amount of force, then experience a declining ability to generate force. It can be a result of vigorous exercise , but abnormal fatigue may be caused by barriers to or interference with the different stages of muscle contraction .

  8. Stress (biology) - Wikipedia

    en.wikipedia.org/wiki/Stress_(biology)

    Physiological stress represents a wide range of physical responses that occur as a direct effect of a stressor causing an upset in the homeostasis of the body. Upon immediate disruption of either psychological or physical equilibrium the body responds by stimulating the nervous, endocrine, and immune systems. The reaction of these systems ...

  9. Synaptic fatigue - Wikipedia

    en.wikipedia.org/wiki/Synaptic_fatigue

    Short-term synaptic depression can affect many synapses of many different types of neurons. [5] The existence and observations of synaptic fatigue are accepted universally, although the exact mechanisms underlying the phenomenon are not completely understood. It is generally seen in mature cells at high frequencies of stimuli (>1 Hz).