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Consolidation chemotherapy is used after initial treatment to target remaining cancer cells. Neoadjuvant chemotherapy is the type used before surgery. Induction chemotherapy is the type used ...
Treatment of acute myeloid leukemia (AML) is typically divided into 2 main phases: A third phase, known as maintenance, is sometimes used after consolidation. Chemotherapy (chemo) is the main treatment for most types of AML, although other treatments might be used as well.
The second phase of chemotherapy is called “consolidation” therapy or "intensification" therapy. The goal of consolidation is to kill any remaining leukemia cells. Consolidation treatment is often based on whether the patient is MRD positive after induction.
Induction is the first phase of treatment. It is short and intensive, typically lasting about a week. The goal is to clear the blood of leukemia cells (blasts) and to reduce the number of blasts in the bone marrow to normal. Consolidation is chemo given after a person has recovered from induction.
Chemotherapy is the main consolidation treatment for AML. Chemotherapy is given soon after remission has been reached (2 to 3 weeks after blood cell counts return to normal). Treatment involves repeating cycles of the same or similar drugs used to bring about the remission.
Consolidation chemotherapy is the second step in treating Acute Myeloid Leukemia (AML). Consolidation chemotherapy happens when we are unable to find signs of leukemia cells in your bone marrow (complete remission).
Consolidation, or intensification, treatment for acute lymphoblastic leukemia (ALL) is given to prevent leukemia cells from coming back. The consolidation treatment phase begins once you go into remission after induction treatment.
Consolidation chemotherapy typically consists of 3 to 4 cycles of cytarabine given in high doses over 5 days in conjunction with additional chemotherapy drugs such as etoposide, daunomycin or idarubicin.
Concurrent chemoradiotherapy (CCRT) is the standard of care for inoperable locally advanced non-small cell lung cancer. To further improve prognosis, the use of consolidation treatments after CCRT has been explored extensively.
The goal of consolidation therapy is to improve the frequency and depth of response without unacceptable toxicity. 1 Modern consolidation therapy typically consists of a triplet or even quadruplet regimen, often but not always identical to the regimen used during induction therapy.