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In histology (microscopic anatomy), the lobules of liver, or hepatic lobules, are small divisions of the liver defined at the microscopic scale. The hepatic lobule is a building block of the liver tissue , consisting of a portal triad, hepatocytes arranged in linear cords between a capillary network, and a central vein .
The falciform ligament, visible on the front of the liver, makes a superficial division of the right and left lobes of the liver. From the underside, the two additional lobes are located on the right lobe. [2] A line can be imagined running from the left of the vena cava and all the way forward to divide the liver and gallbladder into two ...
A liver sinusoid is a type of capillary known as a sinusoidal capillary, discontinuous capillary or sinusoid, that is similar to a fenestrated capillary, having discontinuous endothelium that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.
The hepatic artery provides 30 to 40% of the oxygen to the liver, while only accounting for 25% of the total liver blood flow. The rest comes from the partially deoxygenated blood from the portal vein. The liver consumes about 20% of the total body oxygen when at rest.
It is formed by the union of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). [3] The duct is about 3 cm long. [4] The common hepatic duct is about 6 mm in diameter in adults, with some variation. [5]
The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.
The right hepatic vein is the longest and largest of all the hepatic veins. It drains the liver segments VI and VII in their entirety, and variably participates in the drainage of segments V and VIII; the extent of drainage of the latter two segments by the right hepatic veins as opposed to the middle hepatic vein and possible variant accessory veins determines the calibre of the right hepatic ...
For these purposes, hepatocytes are usually isolated from animal or human [8] whole liver or liver tissue by collagenase digestion, which is a two-step process. In the first step, the liver is placed in an isotonic solution, in which calcium is removed to disrupt cell-cell tight junctions by the use of a calcium chelating agent .
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