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Focal acral hyperkeratosis (also known as "Acrokeratoelastoidosis lichenoides,") is a late-onset keratoderma, inherited as an autosomal dominant condition, characterized by oval or polygonal crateriform papules developing along the border of the hands, feet, and wrists. [8]: 509
It is also typically characterized by the appearance of numerous papules. [3] Injuries can range from small to large plates composed of brown or pink, smooth or hyperkeratotic papules. [ 4 ] The most typical areas where injuries occur are the back of the feet, the toes, the legs, and the area around a venous ulcer formed in the extremities ...
In a clinical setting, it manifests as a single, well-defined, skin-colored papule with a distinctive hyperkeratotic collarette at the base. [5] Though it can also be found in other places like the lower lip, nose, elbow, pre-patellar region, and periungual tissue, it mostly affects the fingers and toes. [6]
The papules usually show up on the patient with an average age of 30 years. [ 1 ] [ 3 ] Kyrle disease is a rare disease unless there is a high count of patients with chronic kidney failure . The disease seems to be more prevalent in African Americans, which can be correlated to the high incidence of diabetes mellitus and kidney failure in the ...
A papule can be flesh colored, yellow, white, brown, black, blue or purplish, or varying shades of red. [4] [6] The intensity of redness might indicate how long the papule has been present. [6] There may be just one or many, and they may occur irregularly in different parts of the body or appear in clusters. [2] It may progress to a pustule or ...
Angiokeratoma of Fordyce (also known as "Angiokeratoma of the scrotum and vulva," though not to be confused with Fordyce's spots) [5] is a skin condition characterized by red to blue papules on the scrotum or vulva. Solitary angiokeratoma is a small, bluish-black, warty papule that occurs predominantly on the lower extremities. [5]: 590
Papulosquamous hyperkeratotic cutaneous conditions are those that present with papules and scales caused by a thickening of the stratum corneum. Subcategories This category has only the following subcategory.
As of yet, the precise etiology of necrolytic acral erythema remains unknown. Numerous causes, including hepatic dysfunction, hypoglucagonemia, hypoalbimunemia, hypoaminoacidemia, zinc deficiency, and diabetes with or without an underlying hepatitis C viral infection, have been postulated as part of the multifactorial pathophysiology of necrolytic acral erythema.