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Focal acral hyperkeratosis (also known as "Acrokeratoelastoidosis lichenoides,") is a late-onset keratoderma, inherited as an autosomal dominant condition, characterized by oval or polygonal crateriform papules developing along the border of the hands, feet, and wrists. [8]: 509
A seborrheic keratosis is a non-cancerous skin tumour that originates from cells, namely keratinocytes, in the outer layer of the skin called the epidermis.Like liver spots, seborrheic keratoses are seen more often as people age.
Angiokeratoma of Fordyce (also known as "Angiokeratoma of the scrotum and vulva," though not to be confused with Fordyce's spots) [5] is a skin condition characterized by red to blue papules on the scrotum or vulva. Solitary angiokeratoma is a small, bluish-black, warty papule that occurs predominantly on the lower extremities. [5]: 590
Imiquimod (Aldara) has been used with success for squamous-cell carcinoma in situ of the skin and the penis, but the morbidity and discomfort of the treatment is severe. An advantage is the cosmetic result: after treatment, the skin resembles normal skin without the usual scarring and morbidity associated with standard excision.
In a clinical setting, it manifests as a single, well-defined, skin-colored papule with a distinctive hyperkeratotic collarette at the base. [5] Though it can also be found in other places like the lower lip, nose, elbow, pre-patellar region, and periungual tissue, it mostly affects the fingers and toes. [ 6 ]
It is also typically characterized by the appearance of numerous papules. [3] Injuries can range from small to large plates composed of brown or pink, smooth or hyperkeratotic papules. [ 4 ] The most typical areas where injuries occur are the back of the feet, the toes, the legs, and the area around a venous ulcer formed in the extremities ...
Porokeratosis may be divided into the following clinical types: [1]: 532 Plaque-type porokeratosis (also known as "Classic porokeratosis" and "Porokeratosis of Mibelli" [2]) is characterized by skin lesions that start as small, brownish papules that slowly enlarge to form irregular, annular, hyperkeratotic or verrucous plaques.
The papules usually show up on the patient with an average age of 30 years. [ 1 ] [ 3 ] Kyrle disease is a rare disease unless there is a high count of patients with chronic kidney failure . The disease seems to be more prevalent in African Americans, which can be correlated to the high incidence of diabetes mellitus and kidney failure in the ...