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Ground-glass opacity (GGO) is a finding seen on chest x-ray (radiograph) or computed tomography (CT) imaging of the lungs. It is typically defined as an area of hazy opacification (x-ray) or increased attenuation (CT) due to air displacement by fluid, airway collapse, fibrosis , or a neoplastic process . [ 1 ]
Acute presentation may reveal poorly defined a micro-nodular interstitial pattern and ground-glass opacities in the lower and mid lung zones. In addition to this, subacute presentations may show reticular nodular opacities in mid-to-lower lung zones. [1] Chronic forms may show fibrotic changes and appear like Idiopathic pulmonary fibrosis. [3]
Clinical tests include chest radiography or (HRCT) which may show centrilobular nodular and ground-glass opacities with air-trapping in the middle and upper lobes of the lungs. Fibrosis may also be evident. Bronchoalveolar Lavage (BAL) findings coinciding with pneumonitis typically include a lymphocytosis with a low CD4:CD8 ratio. [7] [13]
One or more lung nodules can be an incidental finding found in up to 0.2% of chest X-rays [3] and around 1% of CT scans. [ 4 ] The nodule most commonly represents a benign tumor such as a granuloma or hamartoma , but in around 20% of cases it represents a malignant cancer , [ 4 ] especially in older adults and smokers .
Ground-glass opacities are common but less extensive than the reticulation; Distribution characteristically basal and peripheral though often patchy. High-resolution computed tomography scans of the chest of a patient with IPF. The main features are of a peripheral, predominantly basal pattern of coarse reticulation with honeycombing
To confirm the diagnosis, a doctor may perform a lung biopsy using a bronchoscope. Many times, a larger specimen is needed and must be removed surgically. Plain chest radiography shows normal lung volumes, with characteristic patchy unilateral or bilateral consolidation. Small nodular opacities occur in up to 50% of patients and large nodules ...
There may be mild ground-glass opacity; Indeterminate for UIP: [4] Predominantly subpleural and basal; Subtle reticular pattern; May have mild ground-glass opacity or distortion (“early UIP pattern”) Findings suggestive of another diagnosis, including: [4] Other predominant distribution: Peribronchovascular; Perilymphatic; Upper or mid-lung ...
X-ray and CT of ground glass opacities and pneumothorax in pneumocystis pneumonia. [7] Pneumothorax is a well-known complication of PCP. [8] Also, a condition similar to acute respiratory distress syndrome (ARDS) may occur in patients with severe Pneumocystis pneumonia, and such individuals may require intubation. [9]