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Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
[citation needed] Its duration of action is 4 hours with intramuscular injection and 30 minutes with intravenous administration. [citation needed] Mephentermine, along with phentermine, is known to be produced as a metabolite of the orally administered local anesthetic oxetacaine (oxethazaine). [12] [13]
The first store named "Shoppers Drug Mart" was at Shoppers World Danforth from which it derived the name. Koffler revamped the concept of the 20th century drug store in Canada by removing the soda fountain and emphasizing the dispensary, requiring his pharmacists to wear starched white coats as a symbol of their professionalism. In the mid ...
CVS closed 900 stores over three years, citing changes in consumer buying patterns, while Walgreens is planning to close about a quarter of its 8,600 stores because “the current pharmacy model ...
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Big Bear Stores was an American regional supermarket chain operating in the U.S. states of Ohio and West Virginia between 1933 and 2004. The company was founded in Columbus, Ohio, and was headquartered there until its acquisition by Syracuse, New York–based Penn Traffic in 1989.
Chlorphentermine, sold under the brand names Apsedon, Desopimon, and Lucofen, is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the para-chloro derivative of the better-known appetite suppressant phentermine, which is still in current use.
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
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