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Landau–Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, [1] or aphasia with convulsive disorder, is a rare neurological syndrome that develops during childhood. [2] It is named after William Landau and Frank Kleffner, who characterized it in 1957 with a diagnosis of six children. [3] [4]
Conduction aphasia is a mild language disability, and most people return to their normal lives. [10] [13] Broca's and Wernicke's aphasia are commonly caused by middle cerebral artery strokes. [14] Symptoms of conduction aphasia, as with other aphasias, can be transient, sometimes lasting only several hours or a few days.
Aphasia, also known as dysphasia, [a] is an impairment in a person’s ability to comprehend or formulate language because of damage to specific brain regions. [2] The major causes are stroke and head trauma; prevalence is hard to determine, but aphasia due to stroke is estimated to be 0.1–0.4% in developed countries. [3]
Global aphasia is a type of aphasia that occurs in people where a large portion of the language center of the brain has been damaged and results in deficits in all modalities of language. [12] Broca's aphasia, also referred to as expressive aphasia, is an aphasic syndrome in which there is damage in left hemisphere, specifically in the Broca's ...
[1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals. Because most people are not diagnostically trained or knowledgeable, they typically describe their symptoms in layman's terms, rather than using specific medical terminology. This list is not exhaustive.
Transcortical sensory aphasia is characterized as a fluent aphasia. Fluency is determined by direct qualitative observation of the patient’s speech to determine the length of spoken phrases, and is usually characterized by a normal or rapid rate; normal phrase length, rhythm, melody, and articulatory agility; and normal or paragrammatic speech. [5]
Signs and symptoms [ edit ] The acronym "MASA" stands for the four main signs and symptoms associated with the syndrome: (1) mental retardation (mild to moderate intellectual disability), (2) aphasia (delayed onset of speech), (3) shuffling gait , and (4) adducted thumbs [ 4 ] characterized by cleft palate, microcephaly, and dysmyelination. [ 5 ]