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The paramedian pontine reticular formation (PPRF) is a subset of neurons of the oral and caudal pontine reticular nuclei. With the abducens nucleus it makes up the horizontal gaze centre . [ 1 ] It is situated in the pons adjacent to the abducens nucleus . [ 2 ]
It is most frequently caused by lesions such as vascular disease and tumors involving the dorsal pons. Structures affected by the lesion are the dorsal pons (pontine tegmentum) which comprises paramedian pontine reticular formation (PPRF), nuclei of cranial nerves VI and VII , corticospinal tract , medial lemniscus , and the medial longitudinal ...
Infarction; Infections, e.g. Brainstem ... The syndrome usually results from single unilateral lesion of the paramedian pontine reticular formation and the ...
Medial inferior pontine syndrome is a condition associated with a contralateral hemiplegia. [ citation needed ] "Medial inferior pontine syndrome" has been described as equivalent to Foville's syndrome .
The infarction (which arises in the paramedian branches of the anterior spinal artery and/or the vertebral arteries) leads to death of the ipsilateral medullary pyramid, the medial lemniscus, and the hypoglossal nerve fibers that pass through the medulla.
The pontine tegmentum, or dorsal pons, is the dorsal part of the pons located within the brainstem. The ventral part or ventral pons is known as the basilar part of the pons , or basilar pons. Along with the dorsal surface of the medulla oblongata , it forms part of the rhomboid fossa – the floor of the fourth ventricle .
Benedikt syndrome, also called Benedikt's syndrome or paramedian midbrain syndrome, is a rare type of posterior circulation stroke of the brain, with a range of neurological symptoms affecting the midbrain, cerebellum and other related structures. Ipsilateral third nerve palsy presenting with ptosis,abduction of eye. Contralateral flapping tremor.
The disorder is caused by injury or dysfunction in the medial longitudinal fasciculus (MLF), a heavily myelinated tract that allows conjugate eye movement by connecting the paramedian pontine reticular formation (PPRF)-abducens nucleus complex of the contralateral side to the oculomotor nucleus of the ipsilateral side.