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Heat and cold therapy and massage relieve pain by counterstimulation. [ citation needed ] The US Food and Drug Administration defines a counterirritant as "An externally applied substance that causes irritation or mild inflammation of the skin for the purpose of relieving pain in muscles, joints and viscera distal to the site of application.
The diencephalon encloses a cavity called the third ventricle. The thalamus serves as a relay centre for sensory and motor impulses between the spinal cord and medulla oblongata, and the cerebrum. It recognizes sensory impulses of heat, cold, pain, pressure etc. The floor of the third ventricle is called the hypothalamus.
Muscle relaxation and paralysis can theoretically occur by interrupting function at several sites, including the central nervous system, myelinated somatic nerves, unmyelinated motor nerve terminals, nicotinic acetylcholine receptors, the motor end plate, and the muscle membrane or contractile apparatus.
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Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling.Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics.
Endorphins are released from the pituitary gland, typically in response to pain, and can act in both the central nervous system (CNS) and the peripheral nervous system (PNS). In the PNS, β-endorphin is the primary endorphin released from the pituitary gland .
Noxious stimuli activate the endings of nociceptive C and A delta nerve fibers, which carry the signal to neurons in the dorsal horn of spinal cord. DNIC refers to the mechanism by which dorsal horn wide dynamic range neurons responsive to stimulation from one location of the body may be inhibited by noxious stimuli (such as heat, high pressure or electric stimulation) applied to another ...
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