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Tetrahedron Letters is a weekly international journal for rapid publication of full original research papers in the field of organic chemistry. According to the Journal Citation Reports , the journal has a 2022 impact factor of 1.8 [ 1 ]
Tetrahedron is a weekly peer-reviewed scientific journal covering the field of organic chemistry. According to the Journal Citation Reports, Tetrahedron has a 2020 impact factor of 2.1. [1] Tetrahedron and Elsevier, its publisher, support an annual symposium. [2] In 2010, complaints were raised over its high subscription cost. [3]
As a second example, researchers synthesized a cycloprene-modified glutamate photocaged with a 2-nitroveratrol-based PPG. As it is an excitatory amino acid neurotransmitter, the aim was to develop a bioorthagonal probe for glutamate in vivo. [47] In a final example, Venkatesh et al. demonstrated the use of a PPG-based photocaged therapeutic. [48]
The Nozaki–Hiyama–Kishi reaction is a nickel/chromium coupling reaction forming an alcohol from the reaction of an aldehyde with an allyl or vinyl halide. [1] In their original 1977 publication, Tamejiro Hiyama and Hitoshi Nozaki [2] reported on a chromium(II) salt solution prepared by reduction of chromic chloride by lithium aluminium hydride to which was added benzaldehyde and allyl ...
Alfred Hassner [1] [2] was born in Cernăuți and spent World War II in hiding while he lost his father; after the war, he returned to study in Vienna and then immigrated to the USA where he continued his studies. In 1983 he moved with his wife Cyd and two children to Israel.
Example of alkylation of an amine using Shvo's catalyst. Another case of "hydrogen borrowing", the alkylation of amines using other amines is also promoted by Shvo's catalyst. The reaction proceeds through oxidation to an imine, which allows nucleophilic attack, followed by an elimination step and reduction of the double bond.
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Trifluoromethanesulfonyl azide is prepared by treating trifluoromethanesulfonic anhydride with sodium azide, traditionally in dichloromethane. [1] However, the use of dichloromethane is avoided since it can generate highly explosive azido-chloromethane and diazidomethane.