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There are nine essential amino acids which humans must obtain from their diet in order to prevent protein-energy malnutrition and resulting death. They are phenylalanine, valine, threonine, tryptophan, methionine, leucine, isoleucine, lysine, and histidine. [2] [4] There has been debate as to whether there are 8 or 9 essential amino acids. [5]
An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized from scratch by the organism fast enough to supply its demand, and must therefore come from the diet. Of the 21 amino acids common to all life forms, the nine amino acids humans cannot synthesize are valine , isoleucine , leucine , methionine ...
The second column in the following table shows the amino acid requirements of adults as recommended by the World Health Organization [11] calculated for a 62 kg (137 lb) adult. Recommended Daily Intake is based on 2,000 kilocalories (8,400 kJ) per day, [12] which could be appropriate for a 70 kg (150 lb) adult.
The most important aspect and defining characteristic of protein from a nutritional standpoint is its amino acid composition. [43] For all animals, some amino acids are essential (an animal cannot produce them internally so they must be eaten) and some are non-essential (the animal can produce them from other nitrogen-containing compounds ...
Tolerable upper intake levels (UL), to caution against excessive intake of nutrients (like vitamin A and selenium) that can be harmful in large amounts. This is the highest level of sustained daily nutrient consumption that is considered to be safe for, and cause no side effects in, 97.5% of healthy individuals in each life stage and sex group.
The most demanding essential amino acid requirements are for infants, and as children get older and transition into adulthood, the less proportions of essential amino acids they will need. This also means that many of the vegan protein sources that are limited in one or more essential amino acids, are actually less deficient in essential amino ...
Lysine is an essential amino acid in humans. [50] The human daily nutritional requirement varies from ~60 mg/kg in infancy to ~30 mg/kg in adults. [36] This requirement is commonly met in a western society with the intake of lysine from meat and vegetable sources well in excess of the recommended requirement. [36]
The last of the 20 common amino acids to be discovered was threonine in 1935 by William Cumming Rose, who also determined the essential amino acids and established the minimum daily requirements of all amino acids for optimal growth. [15] [16] The unity of the chemical category was recognized by Wurtz in 1865, but he gave no particular name to ...
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