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Diacetyl is reported at lower levels in e-cigarettes than in traditional cigarettes. [238] 2, 3-pentanedione is an α-diketone that is chemically and structurally similar to diacetyl. A 2016 report stated that it had become a popular replacement for diacetyl, although it had been shown to cause airway epithelial damage similar to diacetyl. [179]
There is concern that flavored e-cigarettes could have a similar impact on youth. [14] The extent to which teens are using e-cigarettes may lead to addiction or substance dependence in youth, is unknown. [89] A 2017 review noted that "adolescents experience symptoms of dependence at lower levels of nicotine exposure than adults.
Prior to the outbreak, vitamin E acetate was used in concentrations under 20% of the formula in vape cartridges, as a thickening agent. [19] As a result of a limited availability of cannabis in California, as well as high demand, illicit sellers used 50% or higher concentrations of diluent thickeners to add bulk to low potency cartridges. [19]
In analyzing 51 different flavored e-cigarettes, author of the study Joseph Allen and his team found at least one of three top toxins — diacetyl, acetoin and 2,3-pentanedione — in 47 of the e ...
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The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
E-cigarettes in the U.S. now contain nicotine concentrations that are, on average, more than twice the level allowed in Canada and Europe. The U.S. sets no limits on the nicotine content of any ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 25 January 2025. Device to vaporize substances for inhalation A vaporization heat wand and vaporization chamber bowl used to deliver vapor through a water pipe A vaporizer or vaporiser, colloquially known as a vape, is a device used to vaporize substances for inhalation. Plant substances can be used ...