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Lubiprostone, sold under the brand name Amitiza among others, is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation. The drug is owned by Mallinckrodt and is marketed by Takeda Pharmaceutical Company.
Insulin degludec (INN/USAN) is an ultralong-acting basal insulin analogue that was developed by Novo Nordisk under the brand name Tresiba. [7] It is administered via subcutaneous injection to help control the blood sugar level of those with diabetes .
The National Institute of Health and Care Excellence (NICE) break constipation in adults into two categories: chronic constipation of unknown cause, and constipation due to opiates. [44] In chronic constipation of unknown cause, the main treatment involves the increased intake of water and fiber (either dietary or as supplements). [18]
Megaloblastic anaemia; Methaemoglobinaemia; Erythema multiforme; Low blood sugar; Hepatitis (liver swelling); Crystalluria (crystals in the urine); Urinary obstruction causing difficulty passing urine
Functional constipation, also known as chronic idiopathic constipation (CIC), is defined by less than three bowel movements per week, hard stools, severe straining, the sensation of anorectal blockage, the feeling of incomplete evacuation, and the need for manual maneuvers during feces, without organic abnormalities.
Obstructed defecation syndrome (abbreviated as ODS, with many synonymous terms) is a major cause of functional constipation (primary constipation), [18] of which it is considered a subtype. [19] It is characterized by difficult and/or incomplete emptying of the rectum with or without an actual reduction in the number of bowel movements per week ...
A low-FODMAP diet might help to improve short-term digestive symptoms in adults with irritable bowel syndrome, [120] [114] [121] [20] but its long-term follow-up can have negative effects because it causes a detrimental impact on the gut microbiota and metabolome.
Hypothyroidism can also cause chronic constipation because of sluggish, slower, or weaker colon contractions. Iron supplements or increased blood calcium levels are also potential causes. Spinal cord injury is a common cause of constipation, due to ileus. [citation needed]
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