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Confocal microscopy is the microscopic procedure of choice for examining neuron structures as it produces sharp images with improved resolution and decreased signal-to-noise ratio. The specific way this microscopy works allows one to look at one confocal plane at a time, which is optimal when viewing neuronal structures.
The cells in nervous tissue are densely packed, and little information on their structures and interconnections can be obtained if all the cells are stained. Furthermore, the thin filamentary extensions of neural cells, including the axon and the dendrites of neurons, are too slender and transparent to be seen with normal staining techniques.
Images (3D, 4D) Various No Neuroelectro.org Electrophysiology of neurons Human, others Neuron Electrophysiological properties and data Healthy No [33] Neuromorpho.org 3D models of real neurons Human, rat, mouse, monkey, others Neuron Images and 3D data Healthy No [34] Neuromorphometrics.com: Manually labeled MRI Brain Scans Human Macroscopic
Digital reconstruction or tracing of neuron morphology is a fundamental task in computational neuroscience. [1] [2] [3] It is also critical for mapping neuronal circuits based on advanced microscope images, usually based on light microscopy (e.g. laser scanning microscopy, bright field imaging) or electron microscopy or other methods.
Grey matter, or gray matter in American English, is a major component of the central nervous system, consisting of neuronal cell bodies, neuropil (dendrites and unmyelinated axons), glial cells (astrocytes and oligodendrocytes), synapses, and capillaries.
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White matter forms the bulk of the deep parts of the brain and the superficial parts of the spinal cord. Aggregates of grey matter such as the basal ganglia ( caudate nucleus , putamen , globus pallidus , substantia nigra , subthalamic nucleus , nucleus accumbens ) and brainstem nuclei ( red nucleus , cranial nerve nuclei) are spread within the ...
Pan neuron markers have multiple targets (somatic, nuclear, dendritic, spine and axonal proteins) and consequently label across all parts of the neuron. It is used to study neuronal morphology, although there are specific markers that label particular regions of the neuron.
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