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[47] [48] The chemical name of nortriptyline is 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine and its free base form has a chemical formula of C 19 H 21 N 1 with a molecular weight of 263.384 g/mol. [49] The drug is used commercially mostly as the hydrochloride salt; the free base form is used rarely.
Sodium nitrate has also been investigated as a phase-change material for thermal energy recovery, owing to its relatively high melting enthalpy of 178 J/g. [14] [15] Examples of the applications of sodium nitrate used for thermal energy storage include solar thermal power technologies and direct steam generating parabolic troughs. [14]
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
Sodium nitrite is used as a medication together with sodium thiosulfate to treat cyanide poisoning. [26] It is recommended only in severe cases of cyanide poisoning and has largely been replaced by use of hydroxocobalamin , [ 27 ] a form of vitamin B12 , but given in much higher doses than needed nutritionally. [ 28 ]
Most side effects are direct consequences of the vasodilation and the resultant low blood pressure. They include headache ("nitrate headache") resulting from the widening of blood vessels in the brain, reflex tachycardia (fast heart rate), flush, dizziness, nausea and vomiting. These effects usually subside after a few days if the treatment is ...
The side effects of the TCAs usually come to prominence before the therapeutic benefits against depression and/or anxiety do, and for this reason, they may potentially be somewhat dangerous, as volition can be increased, possibly giving the patient a greater desire to attempt or commit suicide. [10]
The most frequent side effects, occurring in 20% or more of users, are dry mouth, drowsiness, dizziness, constipation, and weight gain (on average 1.8 kg [60]). [23] Other common side effects are headache problems (amblyopia, blurred vision), tachycardia, increased appetite, tremor, fatigue/asthenia/feeling slowed down, and dyspepsia. [23]
It should be used with extreme caution in patients with bipolar disorder due to the potential induction of mania or hypomania. [204] There have been very rare reports of suicidal ideation, but evidence does not support a link. [193] The long-term effects on mental health disorders in later life of chronic use of methylphenidate is unknown. [205]