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  2. Replication crisis - Wikipedia

    en.wikipedia.org/wiki/Replication_crisis

    The replication crisis [a] is an ongoing methodological crisis in which the results of many scientific studies are difficult or impossible to reproduce. Because the reproducibility of empirical results is an essential part of the scientific method , [ 2 ] such failures undermine the credibility of theories building on them and potentially call ...

  3. Reproducibility Project - Wikipedia

    en.wikipedia.org/wiki/Reproducibility_Project

    The project, along with broader action in response to the replication crisis, has helped spur changes in scientific culture and publishing practices. [3] [4] The results of the Reproducibility Project might also affect public trust in psychology.

  4. DNA replication stress - Wikipedia

    en.wikipedia.org/wiki/DNA_replication_stress

    Replication stress and its consequences in mitosis. DNA replication stress refers to the state of a cell whose genome is exposed to various stresses. The events that contribute to replication stress occur during DNA replication, and can result in a stalled replication fork. [1] There are many events that contribute to replication stress ...

  5. DNA re-replication - Wikipedia

    en.wikipedia.org/wiki/DNA_re-replication

    The DNA re-replication response is different from the response taken when damage is due to oxygen radical generation. Damage from oxygen radical generations leads to a response from the Myc oncogene, which phosphorylates p53 and H2AX. [16] The ATM/ATR DNA damage network will also respond to cases where there is an overexpression of Cdt1.

  6. Reproducibility - Wikipedia

    en.wikipedia.org/wiki/Reproducibility

    Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.

  7. Michigan Court declines to hear appeal of ex-officer charged ...

    www.aol.com/michigan-court-declines-hear-appeal...

    The Michigan Supreme Court declined to hear an appeal Monday from a former police officer who is charged with killing a 26-year-old Black man during a traffic stop.. Christopher Schurr was fired ...

  8. Hoda Kotb Talks Possible Future Wedding Almost 3 Years After ...

    www.aol.com/hoda-kotb-talks-possible-future...

    Hoda Kotb is looking ahead towards a possible wedding in her future.. On the Dec. 11 episode of Today with Hoda and Jenna, Kotb and co-host Jenna Bush Hager discussed the "micro-wedding" trend ...

  9. Postreplication repair - Wikipedia

    en.wikipedia.org/wiki/Postreplication_repair

    The replication of DNA with a broken sugar-phosphate backbone is most likely facilitated by the homologous recombination proteins that confer resistance to ionizing radiation. The activity of PRR enzymes is regulated by the SOS response in bacteria and may be controlled by the postreplication checkpoint response in eukaryotes. [8] [9]