Ads
related to: sp100 antigencreative-diagnostics.com has been visited by 10K+ users in the past month
Search results
Results from the WOW.Com Content Network
Sp100 nuclear antigen is an interferon stimulated antigen found in the cell nuclei of many human and higher animal cells. Autoantibodies directed against Sp100 are often found in patients with primary biliary cirrhosis. [1] Histologically Sp100 'dots' regions of the cell nucleus. Viral infection and mitogens affect the expression of the Sp100 ...
Anti-sp100 antibodies are found in association with primary biliary cirrhosis. [1] The autoimmune target of anti-sp100 is the sp100 nuclear antigen which was identified by its association with primary biliary cirrhosis . 20-30% of patients with primary biliary cirrhosis have sp100 Abs.
Expression of PML antigen and sp100 is responsive to interferons. Sp100 seems to have transcriptional transactivating properties. PML protein was reported to suppress growth and transformation, [8] and specifically inhibits the infection of vesicular stomatitis virus (VSV) (a rhabdovirus) and influenza A virus, [18] but not other types of viruses.
The antigens are either from cell extracts or recombinant. Blood serum is incubated in the wells of the plate and is washed out. If antibodies that bind to antigen are present then they will remain after washing. A secondary anti-human antibody conjugated to an enzyme such as horseradish peroxidase is added. The enzyme reaction will produce a ...
Anti-sp100 antibodies [6] Sp100 nuclear antigen: Anti-glycoprotein-210 antibodies [7] nucleoporin 210kDa: Anti-transglutaminase antibodies: Anti-tTG: celiac disease: Anti-eTG: dermatitis herpetiformis: Anti-ganglioside antibodies: ganglioside GQ1B: Miller Fisher syndrome: ganglioside GD3: acute motor axonal neuropathy (AMAN) ganglioside GM1
Sp100 nuclear antigen; T. Tissue transglutaminase; Transglutaminase This page was last edited on 19 September 2016, at 16:21 (UTC). Text is available under the ...
This protein domain has a conserved region of around 80 residues.Mutations in this region lead to various human diseases, particularly in these proteins: Sp100 (Speckled protein 100 kDa), NUDR (Nuclear DEAF-1 related), GMEB (Glucocorticoid Modulatory Element Binding) proteins and AIRE-1 (Autoimmune regulator 1) proteins.
Anti-mitochondrial antibodies (AMA) are autoantibodies, consisting of immunoglobulins formed against mitochondria, [1] primarily the mitochondria in cells of the liver.. The presence of AMA in the blood or serum of a person may be indicative of the presence of, or the potential to develop, the autoimmune disease primary biliary cholangitis (PBC; previously known as primary biliary cirrhosis).
Ads
related to: sp100 antigencreative-diagnostics.com has been visited by 10K+ users in the past month