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Restrictive lung diseases are a category of extrapulmonary, pleural, or parenchymal respiratory diseases that restrict lung expansion, [2] resulting in a decreased lung volume, an increased work of breathing, and inadequate ventilation and/or oxygenation. Pulmonary function test demonstrates a decrease in the forced vital capacity.
The FEV1/FVC ratio, also called modified Tiffeneau-Pinelli index, [1] is a calculated ratio used in the diagnosis of obstructive and restrictive lung disease. [2] [3] It represents the proportion of a person's vital capacity that they are able to expire in the first second of forced expiration to the full, forced vital capacity (). [4]
Restrictive lung diseases yielding from intrinsic factors occur within the lungs themselves, such as tissue death due to inflammation or toxins. Conversely, restrictive lung diseases caused by extrinsic factors result from conditions originating from outside the lungs such as neuromuscular dysfunction and irregular chest wall movements. [6]
Diseases of the Circulatory System VIII 460–519: Diseases of the Respiratory System IX 520–579: Diseases of the Digestive System X 580–629: Diseases of the Genitourinary System XI 630–679: Complications of Pregnancy, Childbirth, and the Puerperium XII 680–709: Diseases of the Skin and Subcutaneous Tissue XIII 710–739
Such scar tissue causes an irreversible decrease in oxygen diffusion capacity, and the resulting stiffness or decreased compliance makes pulmonary fibrosis a restrictive lung disease. [14] Pulmonary fibrosis is perpetuated by aberrant wound healing, rather than chronic inflammation. [15] It is the main cause of restrictive lung disease that is ...
Extrapulmonary restriction is a type of restrictive lung disease, indicated by decreased alveolar ventilation with accompanying hypercapnia.It is characterized as an inhibition to the drive to breathe, or an ineffective restoration of the drive to breathe.
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