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Inheritance of these genes is involved in the etiology (cause) of absence seizure. [1] The commonly held belief is that the genetic factor is the primary cause of childhood absence epilepsy. Furthermore, patients with childhood absence epilepsy have also been reported to exhibit certain copy number variations (CNVs), such as 15q11.2, 15q13.3 ...
Childhood absence epilepsy (CAE), formerly known as pyknolepsy, is an idiopathic generalized epilepsy which occurs in otherwise normal children. The age of onset is between 4–10 years with peak age between 5–7 years. Children have absence seizures which although brief (~4–20 seconds), they occur frequently, sometimes in the hundreds per ...
Breakthrough seizures are more likely with a number of triggers. [54]: 57 Often when a breakthrough seizure occurs in a person whose seizures have always been well controlled, there is a new underlying cause to the seizure. [55] Breakthrough seizures vary. Studies have shown the rates of breakthrough seizures ranging from 11 to 37%. [56]
Brief seizures, such as absence seizures lasting 5–10 seconds, do not cause observable brain damage. [42] More prolonged seizures have a higher risk of neuronal death. [ 42 ] Prolonged and recurrent seizures, such as status epilepticus, typically cause brain damage. [ 42 ]
The seizures can be of the tonic–clonic type, with a regular pattern of contraction and extension of the arms and legs, or of types that do not involve contractions, such as absence seizures or complex partial seizures. [1] Status epilepticus is a life-threatening medical emergency, particularly if treatment is delayed. [1]
Generalized 3 Hz spike and wave discharges in a child with childhood absence epilepsy. Epilepsy is a neurological condition of recurrent episodes of unprovoked epileptic seizures. A seizure is an abnormal neuronal brain activity that can cause
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