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Uterine fibroids, also known as uterine leiomyomas, fibromyoma or fibroids, are benign smooth muscle tumors of the uterus, part of the female reproductive system. [1] Most people [note 1] with fibroids have no symptoms while others may have painful or heavy periods. [1] If large enough, they may push on the bladder, causing a frequent need to ...
When managing leiomyomas, radiation treatment should be avoided due to the inducing effect of malignant transformation in the smooth muscle of the tumor. [11] For uterine leiomyomas, complete removal of the uterus is required. [27] There is minimal evidence to support the use of myomectomy to preserve fertility. [28]
Leiomyoma enucleated from a uterus. External surface on left; cut surface on right. Micrograph of a small, well-circumscribed colonic leiomyoma arising from the muscularis mucosae and showing fascicles of spindle cells with eosinophilic cytoplasm and elongated, cigar-shaped nuclei Immunohistochemistry for β-catenin in uterine leiomyoma, which is negative as there is only staining of cytoplasm ...
A myoma is a type of tumor that involves muscle cells. [1] There are two main types of myoma: Leiomyomas which occur in smooth muscle. [1] They most commonly occur as uterine fibroids, but may also form in other locations.
Leiomyomas are seen in pre-menopausal women and are symptomatic 20–50% of the time, while leiomyosarcomas, the most common uterine sarcomas, are seen in older post-menopausal women [15] with 40-60 being the peak age incidence. [16] Since leiomyomas are benign and mostly asymptomatic, minimally invasive treatment modalities are used to treat ...
Uterine fibroids, also known as uterine leiomyomas, are solid growths of noncancerous smooth muscle cells that are located on the uterus. There is no cause, but risk factors such as family history, reproductive issues, hormones, and viruses are associated with fibroid growth.
Uterine fibroids can be treated with the same methods as sporadic uterine fibroids including anti-hormonal treatment, surgery, or embolisation. Substantially elevated risk of progression to or independent development of uterine leiomyosarcoma has been reported which may influence treatment methods. [3]
Signs and symptoms include spotting, bleeding, abdominal pain, and menstrual cramps. The resulting uterine tissue is called a decidual cast and must be passed through the cervix and vagina. [16] It typically takes the shape of the uterus itself. Membranous dysmenorrhea is extremely rare and there are very few reported cases.