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  2. Valsartan - Wikipedia

    en.wikipedia.org/wiki/Valsartan

    Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs). It is a reasonable initial treatment for high blood pressure. [8] It is taken by mouth. [8]

  3. Sacubitril/valsartan - Wikipedia

    en.wikipedia.org/wiki/Sacubitril/valsartan

    Another 2015 review called the reductions in mortality and hospitalization conferred by sacubitril/valsartan "striking", but noted that its effects in heart failure people with hypertension, diabetes, chronic kidney disease, and the elderly needed to be evaluated further. [40]

  4. Valsartan/hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Valsartan/hydrochlorothiazide

    Valsartan/hydrochlorothiazide, sold under the brand name Diovan HCT among others, is a medication used to treat high blood pressure when valsartan is not sufficient. [6] It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide, a diuretic. [7] It is taken by mouth. [7] Common side effects include dizziness and ...

  5. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. [ 3 ]

  6. Management of hypertension - Wikipedia

    en.wikipedia.org/wiki/Management_of_hypertension

    Guidelines for treating resistant hypertension have been published in the UK [45] and US. [46] It has been proposed that a proportion of resistant hypertension may be the result of chronic high activity of the autonomic nervous system, known as "neurogenic hypertension". [47] Low adherence to treatment is an important cause of resistant ...

  7. Sacubitril - Wikipedia

    en.wikipedia.org/wiki/Sacubitril

    Sacubitril (/ s ə ˈ k juː b ɪ t r ɪ l /; INN) is an antihypertensive drug used in combination with valsartan. The combination drug sacubitril/valsartan, known during trials as LCZ696 and marketed under the brand name Entresto, is a treatment for heart failure. [1] It was approved under the FDA's priority review process for use in heart ...

  8. Labile hypertension - Wikipedia

    en.wikipedia.org/wiki/Labile_hypertension

    Labile hypertension occurs when there are unexpected changes in blood pressure. The term can be used to describe when people have blood pressure measurements that abruptly fluctuate from being abnormally high, approximately 140/90 mm Hg or over and returns to its normal range.

  9. Discovery and development of angiotensin receptor blockers

    en.wikipedia.org/wiki/Discovery_and_development...

    Losartan, valsartan, candesartan, irbesartan, telmisartan and olmesartan all contain a biphenyl-methyl group. [ citation needed ] Losartan is partly metabolized to its 5- carboxylic acid metabolite EXP 3174, which is a more potent AT 1 receptor antagonist than its parent compound [ 17 ] and has been a model for the continuing development of ...

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