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LINE elements propagate by a so-called target primed reverse transcription mechanism (TPRT), which was first described for the R2 element from the silkworm Bombyx mori. ORF2 (and ORF1 when present) proteins primarily associate in cis with their encoding mRNA , forming a ribonucleoprotein (RNP) complex, likely composed of two ORF2s and an ...
LINE1 (an abbreviation of Long interspersed nuclear element-1, also known as L1 and LINE-1) is a family of related class I transposable elements in the DNA of many groups of eukaryotes, including animals and plants, classified with the long interspersed nuclear elements (LINEs). [1]
For example, the 5' of the Alu SINE is derived from 7SL RNA, a sequence transcribed by RNA Polymerase III, giving rise to the RNA element of SRP, an abundant ribonucleoprotein. [6] The body of SINEs possess an unknown origin but often share much homology with a corresponding LINE which thus allows SINEs to parasitically co-opt endonucleases ...
A closed line segment includes both endpoints, while an open line segment excludes both endpoints; a half-open line segment includes exactly one of the endpoints. In geometry , a line segment is often denoted using an overline ( vinculum ) above the symbols for the two endpoints, such as in AB .
Repeated sequences (also known as repetitive elements, repeating units or repeats) are short or long patterns that occur in multiple copies throughout the genome.In many organisms, a significant fraction of the genomic DNA is repetitive, with over two-thirds of the sequence consisting of repetitive elements in humans. [1]
The coordinate-independent definition of the square of the line element ds in an n-dimensional Riemannian or Pseudo Riemannian manifold (in physics usually a Lorentzian manifold) is the "square of the length" of an infinitesimal displacement [2] (in pseudo Riemannian manifolds possibly negative) whose square root should be used for computing curve length: = = (,) where g is the metric tensor ...
Molecular biology – study of biology and biological functions at the molecular level, with some cross over from biochemistry. Structural biology – a branch of molecular biology, biochemistry, and biophysics concerned with the molecular structure of biological macromolecules. Health sciences and human biology – biology of humans.
Immortalised cell lines are widely used as a simple model for more complex biological systems – for example, for the analysis of the biochemistry and cell biology of mammalian (including human) cells. [2] The main advantage of using an immortal cell line for research is its immortality; the cells can be grown indefinitely in culture.