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Glycine (symbol Gly or G; [6] / ˈ ɡ l aɪ s iː n / ⓘ) [7] is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid. Glycine is one of the proteinogenic amino acids. It is encoded by all the codons starting with GG (GGU, GGC, GGA, GGG). [8]
9152 104245 Ensembl ENSG00000165970 ENSMUSG00000039728 UniProt Q9Y345 Q761V0 RefSeq (mRNA) NM_004211 NM_001318369 NM_001146013 NM_148931 RefSeq (protein) NP_001305298 NP_004202 n/a Location (UCSC) Chr 11: 20.6 – 20.66 Mb Chr 7: 49.56 – 49.61 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sodium- and chloride-dependent glycine transporter 2, also known as glycine transporter 2 ...
Atul Malhotra is the director of research for pulmonary, critical care, sleep medicine, and physiology at the University of California, San Diego's Medical School. [1] In addition, he is the Peter C. Farrell Presidential Chair and tenured professor of medicine at the same university. [2]
N-acyl amides are a general class of endogenous fatty acid compounds characterized by a fatty acyl group linked to a primary amine metabolite by an amide bond. Broadly speaking, N-acyl amides fall into several categories: amino acid conjugates (e.g., N-arachidonoyl-glycine), neurotransmitter conjugates (e.g., N-arachidonoyl-serotonin), ethanolamine conjugates (e.g., anandamide), and taurine ...
Glycine N-carboxyanhydride is an organic compound with the formula HNCH(CO) 2 O. A colorless solid, it is the product of phosgenation (reaction with phosgene) of glycine. [4] [5] Glycine N-carboxyanhydride is the simplest member of the amino acid N-carboxyanhydrides. It is also the parent of the 2,5-oxazolidinedione family of heterocycles.
Elevation of extracellular synaptic glycine concentration by blockade of GlyT1 has been hypothesized to potentiate NMDA receptor function in vivo and to represent a rational approach for the treatment of schizophrenia and cognitive disorders. Several drug candidates have reached clinical trials. [9] ASP2535 [10]
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