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  2. Vitamin D5 - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D5

    1α-Hydroxyvitamin D 5 is a chemical derivative of vitamin D 5.The motive to study 1α-hydroxyvitamin D 5 as a potential pharmaceutical drug stemmed from the tendency of calcitriol, a natural metabolite produced in the kidney, to cause toxic hypercalcemia in patients when dosed at concentrations needed to interrupt prostate cancer cells' cycle and stimulate apoptosis.

  3. Vitamin D - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D

    For example, CYP11A1, an enzyme chiefly known for its role in steroidogenesis, has been found to hydroxylate vitamin D3 at several positions, including C-20, C-22, and C-23, without cleaving the side chain. The resulting metabolites, such as 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3, act as inverse agonists for RORα and RORγ2.

  4. 24,25-Dihydroxycholecalciferol - Wikipedia

    en.wikipedia.org/wiki/24,25-Dihydroxycholecalciferol

    24,25-dihydroxyvitamin D 3 is formed from 25-hydroxyvitamin D 3 by the action of CYP24A1 (25-hydroxyvitamin D3-24-hydroxylase). CYP24A1 appears to be "a multicatalytic enzyme catalyzing most, if not all, of the reactions in the C-24/C-23 pathway of 25-OH-D 3 metabolism."

  5. Calcifediol - Wikipedia

    en.wikipedia.org/wiki/Calcifediol

    Calcifediol, also known as calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D 3 (abbreviated 25(OH)D 3), [1] is a form of vitamin D produced in the liver by hydroxylation of vitamin D 3 (cholecalciferol) by the enzyme vitamin D 25-hydroxylase.

  6. To stay healthy, eat more foods with vitamin D, nutrition ...

    www.aol.com/stay-healthy-eat-more-foods...

    A 3½-ounce serving of sockeye salmon contains an average of 670 international units (IU) of vitamin D, more than the recommended daily value for a person under age 70, according to the U.S ...

  7. Vitamin D deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D_deficiency

    Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.

  8. CYP24A1 - Wikipedia

    en.wikipedia.org/wiki/CYP24A1

    CYP24A1 was identified in the early 1970s and was first thought to be involved in vitamin D metabolism as the renal 25-hydroxyvitamin D3-24-hydroxylase, modifying calcifediol (25-hydroxyvitamin D) to produce 24,25-dihydroxycholecalciferol (24,25-dihydroxyvitamin D).

  9. Cholecalciferol - Wikipedia

    en.wikipedia.org/wiki/Cholecalciferol

    This is important for maintaining calcium levels and promoting bone health and development. [4] As a medication, cholecalciferol may be taken as a dietary supplement to prevent or to treat vitamin D deficiency. One gram is 40 000 000 (40 × 10 6) IU, equivalently 1 IU is 0.025 μg, or 25 ng.

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