Search results
Results from the WOW.Com Content Network
This alternate mechanism relies on the direct binding of the 40S ribosomal subunit by the internal ribosome entry site (IRES) in the 5' UTR of HCV RNA. The HCV IRES adopts a complex structure, and may differ significantly from IRES elements identified in picornaviruses. A small number of eukaryotic mRNAs has been shown to be translated by ...
HCV genome. Nonstructural protein 3 (NS3), also known as p-70, is a viral nonstructural protein that is 70 kDa cleavage product of the hepatitis C virus polyprotein. It acts as a serine protease. [1] [2] C-terminal two-thirds of the protein also acts as helicase and nucleoside triphosphatase. [3]
HCV genome. Nonstructural protein 5B (NS5B) is a viral protein found in the hepatitis C virus (HCV). [1] It is an RNA-dependent RNA polymerase, having the key function of replicating HCV's viral RNA by using the viral positive RNA strand as a template to catalyze the polymerization of ribonucleoside triphosphates (rNTP) during RNA replication.
For premium support please call: 800-290-4726 more ways to reach us
The hepatitis C virus (HCV) is a small, enveloped, single-stranded, positive-sense RNA virus. [5] It is a member of the genus Hepacivirus in the family Flaviviridae . [ 19 ] There are seven major genotypes of HCV, which are known as genotypes one to seven. [ 50 ]
The hepatitis C virus (HCV) [3] is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer ( hepatocellular carcinoma , abbreviated HCC) and lymphomas in humans.
The complexity of the HCV genotypes made the treatment specific for the associated genotype. The treatment for the HCV genotype also depends on the presence or absence of cirrhosis. [11] There are six major genotypes of hepatitis C virus which includes many subtypes. [12] The genotype can affect treatment of HCV infections. [3]
Hepacivirus is a genus of positive-strand RNA viruses in the family Flaviviridae. [3] The hepatitis C virus (HCV), in species Hepacivirus C, infects humans and is associated with hepatitis and hepatocellular carcinoma. [3] [4] There are fourteen species in the genus which infect a range of other vertebrate. [3]