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Iguratimod is an anti-inflammatory small molecule drug used for the treatment of rheumatoid arthritis, together with methotrexate in Japan and China. [1] As of 2015 the biological target was not known, but it prevents NF-κB activation and subsequently selectively inhibits COX-2 and several inflammatory cytokines.
Peak concentrations of nirmatrelvir combined with ritonavir following a single dose (300 mg nirmatrelvir and 100 mg ritonavir) in healthy individuals are 2.21 μg/mL while total exposure is 23.01 μg•h/mL. [10]
Initially designated COV2-2196 and COV2-2130, antibody engineering was used to transfer their SARS-CoV-2 binding specificity to IgG scaffolds that would last longer in the body, and these engineered antibodies were named AZD8895 (tixagevimab) and AZD1061 (cilgavimab), respectively (and the combination was called AZD7442). [21]
EvoShield is an American brand that specializes in protective gear. Some of EvoShield products are wrist guards, elbow guards, as well as rib and heart protectors for the sports of baseball , gridiron football , lacrosse and softball .
[5] Drotaverine decreases active ionized calcium supply binding to smooth muscle cells due to inhibition of phosphodiesterase and intracellular accumulation of cAMP . It has an apparent and prolonged action on smooth muscles of internal organs and blood vessels and it moderately decreases arterial blood pressure , increases cardiac output ...
Eltrombopag, sold under the brand name Promacta among others, is a medication used to treat thrombocytopenia (abnormally low platelet counts) and severe aplastic anemia. [3] [4] Eltrombopag is sold under the brand name Revolade outside the US and is marketed by Novartis. [6]
[5] Efavirenz/emtricitabine/tenofovir was approved for medical use in the United States in 2006, [5] [8] and in the European Union in 2007. [6] It is on the World Health Organization's List of Essential Medicines. [9] Efavirenz/emtricitabine/tenofovir is available as a generic medication. [10] [11]
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