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Shigella is a genus of bacteria that is Gram negative, facultatively anaerobic, non–spore-forming, nonmotile, rod shaped, and is genetically nested within Escherichia. The genus is named after Kiyoshi Shiga, who discovered it in 1897. [1] Shigella causes disease in primates, but not in other mammals; it is the causative agent of human ...
Shigella dysenteriae is a species of the rod-shaped bacterial genus Shigella. [1] Shigella species can cause shigellosis (bacillary dysentery). Shigellae are Gram-negative, non-spore-forming, facultatively anaerobic, nonmotile bacteria. [2] S. dysenteriae has the ability to invade and replicate in various species of epithelial cells and ...
This can cause elevated physical temperature, painful spasms of the intestinal muscles , swelling due to fluid leaking from capillaries of the intestine and further tissue damage by the body's immune cells and the chemicals, called cytokines, which are released to fight the infection. The result can be impaired nutrient absorption, excessive ...
Shigellosis, known historically as dysentery, is an infection of the intestines caused by Shigella bacteria. [1] [3] Symptoms generally start one to two days after exposure and include diarrhea, fever, abdominal pain, and feeling the need to pass stools even when the bowels are empty. [1]
The CDC is warning about a rise in an almost untreatable stomach bug, the bacterial infection Shigella, which is a major cause of inflammatory diarrhea. CDC warns about the rise in almost ...
Shigella sonnei is a species of Shigella. [2] Together with Shigella flexneri, it is responsible for 90% of shigellosis cases. [3] Shigella sonnei is named for the Danish bacteriologist Carl Olaf Sonne. [4] [5] It is a Gram-negative, rod-shaped, nonmotile, non-spore-forming bacterium. [6]
Shigella boydii is a Gram-negative bacterium of the genus Shigella. Like other members of the genus, S. boydii is a nonmotile, nonsporeforming, rod-shaped bacterium which can cause dysentery in humans through fecal-oral contamination. [1] [page needed] Shigella boydii is the most genetically divergent species of the genus Shigella. [2]
The bacterial Shiga toxin can be used for targeted therapy of gastric cancer, because this tumor entity expresses the receptor of the Shiga toxin. For this purpose an unspecific chemotherapeutical is conjugated to the B-subunit to make it specific. In this way only the tumor cells, but not healthy cells, are destroyed during therapy. [23]