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The nail matrix is the active tissue (or germinal matrix) that generates cells. The cells harden as they move outward from the nail root to the nail plate. [3] The nail matrix is also known as the matrix unguis, keratogenous membrane, or onychostroma. [4] It is the part of the nail bed that is beneath the nail and contains nerves, lymph and ...
Its function is to protect the area between the nail and epidermis from exposure to bacteria. The vascularization pattern is similar to that of perionychium. [2] In hoofed animals, the eponychium is the deciduous hoof capsule in fetuses and newborn foals, and is a part of the permanent hoof in older animals. [3]
Epidermal stem cells reside in the lower part of the epidermis (stratum basale) and are attached to the basement membrane through hemidesmosomes. Epidermal stem cells divide in a random manner yielding either more stem cells or transit amplifying cells. [ 4 ]
The lunula is the crescent-shape area at the base of the nail, lighter in color as it mixes with matrix cells. Only primates have nails. In other vertebrates, the keratinizing system at the terminus of each digit produces claws or hooves. [2] The epidermis of vertebrates is surrounded by two kinds of coverings, which are produced by the ...
Anatomy of the basic parts of a human nail. In human anatomy, "cuticle" can refer to several structures, but it is used in general parlance, and even by medical professionals, to refer to the thickened layer of skin surrounding fingernails and toenails (the eponychium), and to refer to the superficial layer of overlapping cells covering the hair shaft (cuticula pili), consisting of dead cells ...
The lipids ultimately form the lamellar lipid bilayer that surrounds corneocytes and also contributes to the permeability barrier homeostasis of the stratum corneum. [12] The homeostasis function is regulated by the calcium gradient in the epidermis. [17] Usually the calcium level is very low in stratum corneum, but high in stratum granulosum.
This complex surrounds cells in the stratum corneum and contributes to the skin's barrier function. Corneodesmosomes (modified desmosomes) facilitate cellular adhesion by linking adjacent cells within this epidermal layer. These complexes are degraded by proteases, eventually permitting cells to be shed at the surface. Desquamation and ...
The hyponychium (IPA: / ˌ h aɪ p oʊ ˈ n ɪ k i ə m /) [1] [2] is the area of epithelium, particularly the thickened portion, underlying the free edge of the nail plate on the nail. Its proximal border is immediately distal to distal limit of nail bed—a.k.a. the onychodermal band (the line along the interface of the nail bed and the nail ...