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  2. Loperamide - Wikipedia

    en.wikipedia.org/wiki/Loperamide

    Loperamide, sold under the brand name Imodium, among others, [1] is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea. [ 5 ] [ 4 ] It is often used for this purpose in irritable bowel syndrome , inflammatory bowel disease , short bowel syndrome , [ 4 ] Crohn's disease , and ulcerative colitis . [ 5 ]

  3. Loperamide/simethicone - Wikipedia

    en.wikipedia.org/wiki/Loperamide/simethicone

    It contains loperamide and simethicone. Loperamide is a μ-opioid receptor agonist that works in the intestines. [1] Although it is an opioid, it has no effects on the central nervous system. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the intestinal ...

  4. Antimotility agent - Wikipedia

    en.wikipedia.org/wiki/Antimotility_agent

    By binding to μ-opioid receptors, loperamide inhibits acetylcholine release and decreases excitation of neurons in the myenteric plexus, which leads to a decrease in peristalsis. [4] Decreasing intestinal motility prolongs the transit time of food content through the digestive tract, which allows for more fluid absorption; thereby alleviating ...

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  6. Peripherally selective drug - Wikipedia

    en.wikipedia.org/wiki/Peripherally_selective_drug

    By being excluded from the CNS, drugs may act on the rest of the body without producing side-effects related to their effects on the brain or spinal cord. For example, most opioids cause sedation when given at a sufficiently high dose, but peripherally selective opioids can act on the rest of the body without entering the brain and are less ...

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  8. An experimental drug drove people to lose 23% of their body ...

    www.aol.com/news/novo-nordisk-next-generation...

    CagriSema’s side effects appeared to be similar to other drugs in the GLP-1 class; the company said the most common ones were gastrointestinal, with the “vast majority” mild to moderate and ...

  9. Simeticone - Wikipedia

    en.wikipedia.org/wiki/Simeticone

    Simethicone tablets. Simeticone is used to relieve the symptoms of excessive gas in the gastrointestinal tract, namely bloating, burping, and flatulence. [2] [3] While there is a lack of conclusive evidence that simeticone is effective for this use,⁣ [4] [5] [failed verification] studies have shown that it can relieve symptoms of functional dyspepsia [6] and functional bloating.

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