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The heart is the driver of the circulatory system, pumping blood through rhythmic contraction and relaxation. The rate of blood flow out of the heart (often expressed in L/min) is known as the cardiac output (CO). Blood being pumped out of the heart first enters the aorta, the largest artery of the body.
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. [1] [2] It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek kardia meaning heart, and Latin vascula meaning vessels).
The Heart, arteries, and veins (a network of tubes to carry blood) constitute the cardiovascular system or circulatory system of our body which transports the blood throughout the body. The heart can be thought of as a muscular pump, consisting of four chambers, and pulsatile muscles which pump and circulates the blood through the vasculature.
This part of coronary circulatory regulation is known as auto regulation and it occurs over a plateau, reflecting the constant blood flow at varying CPP & resistance. The slope of a CBF (coronary blood flow) vs. CPP graph gives 1/Resistance. Autoregulation maintains a normal blood flow within the pressure range of 70–110 mm Hg.
The circulatory system uses the channel of blood vessels to deliver blood to all parts of the body. This is a result of the left and right sides of the heart working together to allow blood to flow continuously to the lungs and other parts of the body. Oxygen-poor blood enters the right side of the heart through two large veins.
The narrowing of blood vessels leads to an increase in peripheral resistance, thereby elevating blood pressure. While vasoconstriction is a normal and essential regulatory mechanism for maintaining blood pressure and redistributing blood flow during various physiological processes, its dysregulation can contribute to pathological conditions.
The programmed delay at the AV node also provides time for blood volume to flow through the atria and fill the ventricular chambers—just before the return of the systole (contractions), ejecting the new blood volume and completing the cardiac cycle. [8] (See Wiggers diagram: "Ventricular volume" tracing (red), at "Systole" panel.)
When blood vessels dilate, the flow of blood is increased due to a decrease in vascular resistance and increase in cardiac output [further explanation needed]. Vascular resistance is the amount of force circulating blood must overcome in order to allow perfusion of body tissues. Narrow vessels create more vascular resistance, while dilated ...