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Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. [ 3 ] [ 4 ] Generally it is used together with dietary changes and a statin . [ 5 ]
It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US). Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine and inhibiting the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.
The first study involved 382 participants also taking the maximum tolerated doses of statins. [2] After three months, LDL cholesterol levels were reduced by 36% in participants taking bempedoic acid and ezetimibe compared with a reduction of 23% with ezetimibe alone, 17% with bempedoic acid alone and an increase of around 2% with placebo (a ...
Others reported that they had experienced side effects including sleep paralysis and next-day drowsiness. There were also reports of suicidal thoughts and attempts, two of which were successful. Merck correctly points out that the side effects correspond to the ones the company included on the warning label.
Rhino pills and other non-prescription supplements aren’t regulated by the U.S. Food and Drug Administration (FDA) like medications are, and there’s rarely much science to back their claims ...
People with sleep apnea start and stop breathing while they sleep, and snoring is a common side effect. "Sleep apnea is one of the most under-recognized cardiac risk factors in cardiology," says ...
“The best ways to improve sleep are simple but effective: maintain a regular sleep schedule, limit screen time before bed, and create a calm, cool, and dark sleep environment,” she says.
However, as per a review by the National Institute for Health and Clinical Excellence (NICE), inadequate evidence supports the use of Z-drugs for treating insomnia. The review noted that clinical trials inappropriately compared short-acting nonbenzodiazepines with long-acting benzodiazepines, and there is a lack of studies that compare the ...
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