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Hyphema is the medical condition of bleeding in the anterior chamber of the eye between the iris and the cornea. [1] People usually first notice a loss or decrease in vision. [1] The eye may also appear to have a reddish tinge, or it may appear as a small pool of blood at the bottom of the iris in the cornea.
A subconjunctival hemorrhage appears as a bright red patch on the white of the eye and is commonly referred to as a burst blood vessel. In hyphema, blood pools in the anterior chamber, where the iris (the colored part of the eye) and the pupil are located. Hyphemas are graded based on the amount of blood covering the cornea.
The anterior chamber is the aqueous humor-filled space inside the eye between the iris and the cornea's innermost surface, the endothelium. [1] Hyphema, anterior uveitis and glaucoma are three main pathologies in this area. In hyphema, blood fills the anterior chamber as a result of a hemorrhage, most commonly after a blunt eye injury.
Uveitis–glaucoma–hyphaema (UGH) syndrome, also known as Ellingson syndrome, is a complication of cataract surgery, caused by intraocular lens subluxation or dislocation. The chafing of mispositioned intraocular lens over iris , ciliary body or iridocorneal angle cause elevated intraocular pressure (IOP) anterior uveitis and hyphema .
Neovascularisation (growth of new abnormal vessels) is possible and any eye surgery, such as cataract surgery, can cause bleeding from the fragile vessels in the atrophic iris causing accumulation of blood in the anterior chamber of the eye, also known as hyphema.
It is an exudate rich in white blood cells, seen in the anterior chamber, usually accompanied by redness of the conjunctiva and the underlying episclera. It is a sign of inflammation of the anterior uvea and iris, i.e. iritis, which is a form of anterior uveitis. The exudate settles at the dependent aspect of the eye due to gravity.
Amsler sign also known as Amsler–Verrey sign is the name of the diagnostic finding seen in people with Fuchs heterochromic iridocyclitis (FHI). It is described as presence of blood in the aspirated aqueous fluid, in paracentesis of the anterior chamber, and is caused due to iris atrophy usually seen in FHI and exposure of the fragile iris vasculature to the aqueous fluid.
The depth of the anterior chamber and position of the posterior capsule may be maintained during surgery by OVDs or an anterior chamber maintainer, which is an auxiliary cannula providing a sufficient flow of BSS to maintain the stability of the shape of the chamber and internal pressure. [4] [9] [clarification needed]