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Colorectal cancer has a prevalence of 7% at 30 years after diagnosis and accounts for 15% of deaths in people with Crohn's. Risk is higher if the disease occurs in most of the colon. Endoscopic surveillance is performed to detect and remove polyps, while surgery is required for dysplasia beyond the mucosal surface. [19]
People with inflammatory bowel disease account for less than 2% of colon cancer cases yearly. [33] In those with Crohn's disease, 2% get colorectal cancer after 10 years, 8% after 20 years, and 18% after 30 years. [33] In people who have ulcerative colitis, approximately 16% develop either a cancer precursor or cancer of the colon over 30 years ...
The corresponding relative risk is 1.5 for lung cancer, [82] and 1.9 for prostate cancer. [83] For breast cancer, the relative risk is 1.8 with a first-degree relative having developed it at 50 years of age or older, and 3.3 when the relative developed it when being younger than 50 years of age. [84]
Hereditary nonpolyposis colorectal cancer (HNPCC) is a hereditary predisposition to colon cancer.. HNPCC includes (and was once synonymous with) [1] Lynch syndrome, an autosomal dominant genetic condition that is associated with a high risk of colon cancer, endometrial cancer (second most common), ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. [2]
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. [1] It is a long-term condition that results in inflammation and ulcers of the colon and rectum.
The increased risk is believed to be primarily due to the same risk factors that produced the first cancer, such as the person's genetic profile, alcohol and tobacco use, obesity, and environmental exposures, and partly due, in some cases, to the treatment for the first cancer, which might have included mutagenic chemotherapeutic drugs or ...
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Exudative diarrhea occurs with the presence of blood and pus in the stool. This occurs with inflammatory bowel diseases, such as Crohn's disease or ulcerative colitis, and other severe infections such as E. coli or other forms of food poisoning. [19] [18]
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