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Absolute specificity can be thought of as being exclusive, in which an enzyme acts upon one specific substrate. [8] Absolute specific enzymes will only catalyze one reaction with its specific substrate. For example, lactase is an enzyme specific for the degradation of lactose into two sugar monosaccharides, glucose and galactose.
The characteristic properties of a substance are always the same whether the sample being observed is large or small. Thus, conversely, if the property of a substance changes as the sample size changes, that property is not a characteristic property. Examples of physical properties that aren't characteristic properties are mass and volume.
A comparison of specificity constants can also be used as a measure of the preference of an enzyme for different substrates (i.e., substrate specificity). The higher the specificity constant, the more the enzyme "prefers" that substrate. [1] The following equation, known as the Michaelis–Menten model, is used to describe the kinetics of enzymes:
Each active site is evolved to be optimised to bind a particular substrate and catalyse a particular reaction, resulting in high specificity. This specificity is determined by the arrangement of amino acids within the active site and the structure of the substrates. Sometimes enzymes also need to bind with some cofactors to fulfil their function.
The invariance properties of molecular descriptors can be defined as the ability of the algorithm for their calculation to give a descriptor value that is independent of the particular characteristics of the molecular representation, such as atom numbering or labeling, spatial reference frame, molecular conformations, etc. Invariance to molecular numbering or labeling is assumed as a minimal ...
Atomic species: Specific form of an element defined by the atom's isotope, electronic or oxidation state. Argon is an atomic species of formula Ar. [5] Molecular species: Groups of atoms that are held together by chemical bonds. An example is ozone, which has the chemical formula O 3. [6]
Specific energy has the same units as specific strength, which is related to the maximum specific energy of rotation an object can have without flying apart due to centrifugal force. The concept of specific energy is related to but distinct from the notion of molar energy in chemistry , that is energy per mole of a substance, which uses units ...
Chemical similarity (or molecular similarity) refers to the similarity of chemical elements, molecules or chemical compounds with respect to either structural or functional qualities, i.e. the effect that the chemical compound has on reaction partners in inorganic or biological settings.